I finally took the plunge, after 8 years. All vivtek.com mail is now going through the Despammed filters. I just couldn't take the sheer mass of spam any more. (I get more than 1000 email spam messages a day and yes, for 8 years I've sorted through them by hand. Did I mention I read quickly? But lately I've been letting the spam slush pile get too big. Time for a change.)
There are some issues I still want to address -- like setting up a whitelist for customers to be on the very safe side -- but I have to say that the drop in spam in my actual Inbox has been (1) incredible and (2) so worth it.